Product Details
| ISBN-13 | 9780470584927 |
|---|---|
| ISBN-10 | 0470584920 |
| Authors | Thomas N. Seyfried, PhD |
| Publisher | Wiley |
| Publication date | 2012 |
| Format | Hardcover |
| Language | English |
| Pages | 448 |
| Category | Medicine & Healthcare |
| List price | $54.99 / copy |
| Min. order | 5 copies |
| Condition | New |
Description
Cancer as a Metabolic Disease by Thomas N. Seyfried presents the case that cancer is fundamentally a metabolic disorder driven by mitochondrial dysfunction, expanding on Otto Warburg's energy-metabolism theory. Cancer biology, biochemistry, and oncology programs can source it in bulk directly through Global Academic Supply.
Key Features
- Hardcover, Wiley, 2012, 448 pages
- Links Warburg's energy-metabolism theory of cancer to the modern hallmarks of cancer
- Covers respiratory dysfunction, mitochondrial glutamine fermentation, the retrograde response, and mitochondria as tumor suppressor
- Addresses metastasis, extrachromosomal origins, evolutionary perspectives, and treatment/metabolic management strategies
- Brain cancer case studies presented as proof of principle, with parallels drawn to breast and colon cancer
- Publisher list price $275.95
Specifications
- Author: Thomas N. Seyfried, PhD
- Publisher: Wiley
- Format: Hardcover, 448 pages
- ISBN-13: 9780470584927
- ISBN-10: 0470584920
- Publication date: 2012
Buy in Bulk from Global Academic Supply
Cancer as a Metabolic Disease is available to order through Global Academic Supply at $52.99 per copy for 5+, $49.99 for 10+, and $46.99 for 25+, against a $54.99 list price. Institutions can pay by purchase order with Net-30 terms, and tax-exempt certificates are accepted for qualifying organizations.
About This Edition
Written by Thomas N. Seyfried, PhD (Yale, Boston College), Cancer as a Metabolic Disease challenges the dominant genetic-mutation theory of cancer with a mitochondrial/metabolic origin argument. It is a natural bulk title for cancer biology and oncology programs studying alternative and metabolic approaches to cancer.
Key Topics
- Hardcover, Wiley, 2012, 448 pages
- Links Warburg's energy-metabolism theory of cancer to the modern hallmarks of cancer
- Covers respiratory dysfunction, mitochondrial glutamine fermentation, the retrograde response, and mitochondria as tumor suppressor
- Addresses metastasis, extrachromosomal origins, evolutionary perspectives, and treatment/metabolic management strategies
- Brain cancer case studies presented as proof of principle, with parallels drawn to breast and colon cancer
- Publisher list price $275.95
Who This Is For
- Cancer biology, biochemistry, and oncology programs studying the metabolic (mitochondrial dysfunction) theory of cancer origin and management.
Table of Contents
- Images of Cancer
- Confusion Surrounds the Origin of Cancer
- Cancer Models
- Energetics of Normal Cells and Cancer Cells
- Respiratory Dysfunction in Cancer Cells
- The Warburg Dispute
- Is Respiration Normal in Most Cancer Cells?
- Is Mitochondrial Glutamine Fermentation the Missing Link in the Metabolic Theory of Cancer?
- Genes, Respiration, Viruses, and Cancer
- Respiratory Insufficiency, the Retrograde Response, and the Origin of Cancer
- Mitochondria: The Ultimate Tumor Suppressor
- Abnormalities in Growth Control, Telomerase Activity, Apoptosis, and Angiogenesis
- Metastasis
- Extrachromosomal Origin of Cancer
- Evolutionary Perspectives
- Treatment Strategies
- Metabolic Management
- Patient Implementation
- Cancer Prevention
- Case Studies
Institutional & Bulk Ordering
- Minimum order: 5 copies, with tiered pricing at higher quantities
- Purchase orders and Net-30 terms accepted for qualifying institutions
- Tax-exempt certificates accepted at checkout
- Free worldwide shipping, no sales tax
Edition & Identifier Check
Always confirm this exact ISBN-13 and edition (9780470584927) against your syllabus or procurement request before ordering — editions of this title are not interchangeable.
Frequently Asked Questions
Q: Who is this book for?
A: Cancer biology, biochemistry, and oncology programs studying the metabolic (mitochondrial dysfunction) theory of cancer origin and management.
Q: What edition and format is this?
A: Hardcover, published by Wiley in 2012, 448 pages.
Q: What does this book argue?
A: That cancer is fundamentally a metabolic disorder driven by mitochondrial dysfunction, expanding on Otto Warburg's energy-metabolism theory and linking it to the modern hallmarks of cancer, with case studies (including brain cancer) presented as proof of principle for metabolic management and prevention strategies.
Q: What bulk pricing tiers apply to this title?
A: $52.99 per copy for 5+, $49.99 for 10+, $46.99 for 25+, and a custom quote at 100+, against a $54.99 list price.
Q: Is it in stock for a bulk order?
A: Yes, it's currently in stock and available for bulk order.